Kötting, Oliver, Dr.

Education

Ph.D. in Molecular Plant Physiology (magna cum laude), 18th August 2005. Institute of Biochemistry and Biology, University of Potsdam, Germany. Thesis title: A novel starch-related enzyme in Arabidopsis thaliana: The phosphoglucan, water dikinase. Supervisor: Dr. G. Ritte. Referees: Prof. M. Steup, Prof. U.-I. Flügge, Prof. N. Amrhein.

Diploma in biology (first class, 1.0, 100%), 6th April 2001. University of Bonn, Germany. Main subjects: cell biology, biochemistry, genetics. Thesis title: Protein interactions between components of the alternative Sec-complex in the membrane of the endoplasmic reticulum of the yeast Saccharomyces cerevisiae. Referees: Prof. V. Herzog, Dr. habil. N. Johnsson.

Assistant Biological Technician, 4th July 1995. Rheinische Akademie e. V., Cologne, Germany. Vocational training at a private university of applied science.

University entrance diploma (Abitur), 16th June 1993. Schiller-Gymnasium, Witten, Germany.

Professional Experience

Grants

Kötting O., Gentry M.S., Zeeman S.C. (2010) A proteomics approach to identify novel mechanisms causing a fatal progressive myoclonus epilepsy – Lafora disease A research project within the programme “Rare Diseases – New Approaches” by GEBERT RÜF STIFTUNG, GRS-049/10, CHF 250’000.

Publications

2012

Glaring M.A., Skryhan K., Kötting O., Zeeman S.C., Blennow A. (2012) Comprehensive survey of redox sensitive starch metabolising enzymes in Arabidopsis thaliana. Plant Physiology and Biochemistry. Plant Physiology and Biochemistry, 58, 89-97. [pdf]

Hädrich N., Hendriks J., Kötting O., Arrivault S., Feil R., Zeeman S. C., Gibon Y., Schulze W., Stitt M., Lunn J. (2012) Mutagenesis of cysteine-81 prevents dimerisation of the APS1 subunit of ADP-glucose pyrophosphorylase and alters diurnal starch turnover in Arabidopsis thaliana leaves. The Plant Journal, 70, 231-242. [pdf]

2011

Santelia D., Kötting O., Seung D., Schubert M., Thalmann M., Bischof S., Meekins D.A., Lutz A., Patron N., Gentry M. S., Allain F.H.-T., Zeeman S.C. (2011) The phosphoglucan phosphatase LSF2 (Like Sex Four 2) dephosphorylates starch at the C3-position in Arabidopsis. Plant Cell, 23, 4096-4111. [pdf]

Hostettler C., Kölling K., Santelia D., Streb S., Kötting O., Zeeman S.C. (2011) Analysis of starch metabolism in chloroplasts. Methods in Molecular Biology, 775, 387-410. [pdf]

2010

Comparot-Moss S., Kötting O., Stettler M., Edner C., Graf A., Weise S.E., Streb S., Lue W.-L., MacLean D.l, Mahlow S., Ritte G., Steup M., Chen J., Zeeman S.C., Smith A.M. (2010) A putative phosphatase, LSF1, is required for normal starch turnover in Arabidopsis leaves. Plant Physiology, 152, 685-697. [pdf]

Hejazi M., Fettke J., Kötting O., Zeeman S.C., Steup M. (2010) The laforin-like dual-specificity phosphatase SEX4 from Arabidopsis thaliana hydrolyses both C6- and C3-phosphate esters introduced by starch-related dikinases and thereby affects phase transition of α-glucans. Plant Physiology, 152, 711-722 . [pdf]

Kötting O., Kossmann J., Zeeman S.C., Lloyd J.R. (2010) Regulation of starch metabolism: The age of enlightenment? Current Opinion in Plant Biology, 13, 321-329. [pdf]

2009

Kötting O., Santelia D., Edner C., Eicke S., Marthaler T., Gentry M.S., Comparot- Moss S., Chen J., Smith A.M., Steup M., Ritte G., Zeeman S.C. (2009) STARCH-EXCESS4 is a laforin-like phosphoglucan phosphatase required for starch degradation in Arabidopsis thaliana. The Plant Cell, 21, 334-346. [pdf]

2007

Zeeman S.C., Delatte T., Messerli G., Umhang M., Stettler M., Mettler T., Streb S., Reinhold H., Kötting O. (2007) Starch breakdown: recent discoveries suggest distinct pathways and novel mechanisms. Functional Plant Biology, 34, 465-473. [pdf]

2006

Ritte G., Heydenreich M., Mahlow S., Haebel S., Kötting O., Steup M. (2006) Phosphorylation of C6- and C3-positions of glucosyl residues in starch is catalysed by distinct dikinases. FEBS Letters, 580, 4872-4876.
[pdf]

Fettke J., Eckermann N., Kötting O., Ritte G., Steup M. (2006) Novel starch-related enzymes and carbohydrates. Cellular and Molecular Biology, 52 Suppl., OL883-904.
[pdf]

2005

Kötting O., Pusch K., Tiessen A., Geigenberger P., Steup M., Ritte G. (2005) Identification of a novel enzyme required for starch metabolism in Arabidopsis leaves. The phosphoglucan, water dikinase. Plant Physiology, 137, 242-252.
[pdf]

Selected Talks

2010

Kötting O. (2010) Interactions between enzymes involved in starch degradation in Arabidopsis. In Photosynthetic Carbohydrate Partitioning. Stellenbosch, South Africa: 26th November 2010.

Kötting O. (2010) New aspects of starch metabolism: Reversible starch phosphorylation and protein-protein interactions. In Plant Physiology Seminar. University of Osnabrück, Germany: 9th July 2010.

Kötting O. (2010) The role of reversible glucan phosphorylation in the control of starch degradation. In FOR 1061, 1st International Meeting; Plant Primary Metabolism: Synthesis, Storage and Degradation Processes. Waldfischbach, Germany: 19th-21st May 2010.

2009

Kötting O. (2009) The role of reversible glucan phosphorylation in starch metabolism. In Starch Round Table. Baltimore, MD, USA: 10th-12th September 2009.

Kötting O. (2009) Reversible glucan phosphorylation, a previously unknown mechanism, is essential for starch metabolism in Arabidopsis.
In 22nd Meeting ‘Molekularbiologie der Pflanzen’. Dabringhausen, Germany: 17th-20th February 2009.

2008

Kötting O.(2008) SEX4, a glucan phosphatase, dephosphorylates amylopectin in Arabidopsis leaves. In 5th Tri-National Arabidopsis Meeting. Zurich, Switzerland: 10th-13th September 2008.

Kötting O. (2008) Reversible starch phosphorylation: a previously unknown mechanism regulating starch metabolism in Arabidopsis thaliana.
In 17th Swiss Plant Molecular and Cell Biology Conference. Les Diablerets, Switzerland: 6th-8th February 2008.

Patents

Frohberg C., Kötting O., Ritte G., Steup M. (2005) Plants with increased activity of a starch phosphorylating enzyme. EU Patent, PCT/EP2005/002449.

Frohberg C., Kötting O., Ritte G., Steup M. (2005) Plants with reduced activity of a starch phosphorylating enzyme. EU Patent, PCT/EP2005/002450.

Frohberg C., Kötting O., Ritte G., Steup M. (2005) Methods for identifying proteins with starch phosphorylating enzymatic activity. EU Patent, PCT/EP2005/002454.

Frohberg C., Kötting O., Ritte G., Steup M. (2005) Plants with increased activity of multiple starch phosphorylating enzymes. EU Patent, PCT/EP2005/002457.